Glycosidic prodrugs of highly potent bifunctional duocarmycin derivatives for selective treatment of cancer

Angew Chem Int Ed Engl. 2010 Sep 24;49(40):7336-9. doi: 10.1002/anie.201002502.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents / chemistry*
  • Antineoplastic Agents / pharmacology
  • Cell Line, Tumor
  • Duocarmycins
  • Glycosides / chemistry*
  • Humans
  • Indoles / chemistry*
  • Indoles / therapeutic use
  • Inhibitory Concentration 50
  • Molecular Structure
  • Neoplasms / drug therapy*
  • Prodrugs / chemistry*
  • Prodrugs / pharmacology
  • Pyrrolidinones / chemistry
  • Pyrrolidinones / therapeutic use

Substances

  • Antineoplastic Agents
  • Duocarmycins
  • Glycosides
  • Indoles
  • Prodrugs
  • Pyrrolidinones
  • duocarmycin A