Effect of eutectic mixture of local anesthetics on pain perception during scaling by ultrasonic or hand instruments: a masked randomized controlled trial

J Periodontol. 2011 Feb;82(2):259-66. doi: 10.1902/jop.2010.090748. Epub 2010 Aug 23.

Abstract

Background: The aims of this study are to evaluate the efficacy of a eutectic mixture of local anesthetic (EMLA) cream on pain perception during scaling and to compare the intensities of pain provoked by hand and ultrasonic instruments.

Methods: Forty subjects with chronic gingivitis or periodontitis were enrolled in the study. In this randomized, split-mouth, controlled, masked clinical trial, each of the four quadrants in subjects was randomly assigned to receive one of the following protocols: scaling with an ultrasonic scaler with or without the application of the EMLA cream or scaling with a Gracey curet with or without the application of the EMLA cream. Pain levels after each quadrant of scaling were assessed with a visual analog scale (VAS; 0 to 100 mm) and verbal rating score (VRS; 0 to 4). All subjects were recalled to detect any complications after 24 hours.

Results: The mean VAS and VRS when EMLA cream was applied (18.39 ± 14.47 mm and 0.95 ± 0.69) were significantly lower (P <0.001 for VAS and VRS) compared to when EMLA cream was not used (26.54 ± 16.46 mm and 1.30 ± 0.75). The mean VAS and VRS of the ultrasonic scaler group (20.43 ± 16.40 mm and 0.98 ± 0.76) were significantly lower (P = 0.024 for VAS; P = 0.003 for VRS) than those of the Gracey curet group (24.50 ± 15.17 mm and 1.28 ± 0.69). None of the subjects showed adverse effects after EMLA-cream application.

Conclusion: Although most patients experienced limited pain during scaling, a significant reduction of pain is achieved by using EMLA cream and ultrasonic scaler.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Analysis of Variance
  • Anesthetics, Combined / therapeutic use
  • Anesthetics, Local / therapeutic use*
  • Dental Instruments
  • Drug Combinations
  • Female
  • Follow-Up Studies
  • Gingivitis / complications
  • Gingivitis / therapy*
  • Humans
  • Lidocaine / therapeutic use*
  • Lidocaine, Prilocaine Drug Combination
  • Male
  • Matched-Pair Analysis
  • Middle Aged
  • Pain / drug therapy*
  • Pain / etiology
  • Pain Perception / drug effects
  • Periodontitis / complications
  • Periodontitis / therapy*
  • Prilocaine / therapeutic use*
  • Root Planing / adverse effects
  • Root Planing / instrumentation*
  • Root Planing / methods
  • Single-Blind Method
  • Treatment Outcome
  • Ultrasonic Therapy
  • Young Adult

Substances

  • Anesthetics, Combined
  • Anesthetics, Local
  • Drug Combinations
  • Lidocaine, Prilocaine Drug Combination
  • Prilocaine
  • Lidocaine