The results of the colon cancer treatment with the use of laparoscopic surgery and different radiotherapy regimens were compared. 75 patients were observed. The main group consisted of 38 patients, who were operated on laparoscopically and had received neoadjuvant radiotherapy course. The control group consisted of 37 patients. The were operated on with the use of "open" techniques, had been colostomized before radical surgery and received adjuvant radiotherapy course. Laparoscopic technologies allowed to improve immediate results of the treatment and to decrease the complication rate from 17.2 to 8.2%. Neoadjuvant radiotherapy allowed to decrease the rate of local cancer recurrence from 28.8 to 12.55%.