Novel phosphatase PHLPP-1 regulates mitochondrial Akt activity and cardiac cell survival

Circ Res. 2010 Aug 20;107(4):448-50. doi: 10.1161/CIRCRESAHA.110.225896.
No abstract available

Publication types

  • Comment
  • Editorial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cell Survival / physiology
  • Enzyme Activation / genetics
  • Enzyme Activation / physiology
  • Humans
  • Mitochondria, Heart / enzymology*
  • Mitochondrial Proteins / physiology*
  • Myocytes, Cardiac / cytology*
  • Myocytes, Cardiac / enzymology*
  • Nuclear Proteins / deficiency
  • Nuclear Proteins / genetics
  • Nuclear Proteins / physiology*
  • Oncogene Protein v-akt / metabolism*
  • Phosphoprotein Phosphatases / deficiency
  • Phosphoprotein Phosphatases / genetics
  • Phosphoprotein Phosphatases / physiology*

Substances

  • Mitochondrial Proteins
  • Nuclear Proteins
  • Oncogene Protein v-akt
  • PHLPP1 protein, human
  • Phosphoprotein Phosphatases