The intestinal microbiome: relationship to type 1 diabetes

Josef Neu; Graciela Lorca; Sandra D K Kingma; Eric W Triplett

doi:10.1016/j.ecl.2010.05.008

The intestinal microbiome: relationship to type 1 diabetes

Endocrinol Metab Clin North Am. 2010 Sep;39(3):563-71. doi: 10.1016/j.ecl.2010.05.008.

Authors

Josef Neu¹, Graciela Lorca, Sandra D K Kingma, Eric W Triplett

Affiliation

¹ Department of Pediatrics, University of Florida, Gainesville, FL 326101, USA. neuj@peds.ufl.edu

PMID: 20723820
DOI: 10.1016/j.ecl.2010.05.008

Abstract

This article discusses recent evidence that associates the developing intestinal microbiome to the pathogenesis of autoimmune T1D. It attempts to identify avenues that should be pursued that relate this new evidence to interventions that eventually could result in prevention.

Publication types

Review

MeSH terms

Diabetes Mellitus, Type 1 / etiology*
Diabetes Mellitus, Type 1 / immunology
Diabetes Mellitus, Type 1 / microbiology*
Food
Humans
Intestines / drug effects
Intestines / immunology
Intestines / microbiology*
Metagenome / drug effects
Metagenome / immunology
Metagenome / physiology*
Models, Biological
Probiotics / pharmacology