Abstract
The dopamine transporter (DAT) is a transmembrane protein responsible for reuptake of dopamine from the synaptic cleft and termination of dopaminergic transmission. Several radioligands are available for DAT imaging with SPECT and PET. This review summarizes the main SPECT and PET radioligands and the main applications of DAT imaging in neuropsychiatric disorders.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Attention Deficit Disorder with Hyperactivity / diagnosis
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Attention Deficit Disorder with Hyperactivity / metabolism
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Biomarkers / metabolism
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Dopamine / deficiency
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Dopamine Plasma Membrane Transport Proteins / metabolism*
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Humans
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Molecular Imaging / methods*
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Parkinson Disease / diagnosis
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Parkinson Disease / metabolism
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Parkinson Disease / therapy
Substances
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Biomarkers
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Dopamine Plasma Membrane Transport Proteins
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Dopamine