Biocatalytic desymmetrization of an atropisomer with both an enantioselective oxidase and ketoreductases

Angew Chem Int Ed Engl. 2010 Sep 17;49(39):7010-3. doi: 10.1002/anie.201002580.

Authors

Bo Yuan¹, Abigail Page, Christopher P Worrall, Franck Escalettes, Simon C Willies, Joseph J W McDouall, Nicholas J Turner, Jonathan Clayden

Affiliation

¹ School of Chemistry, University of Manchester, Manchester Interdisciplinary Biocentre, 131 Princess Street, Manchester M1 7DN, UK.

PMID: 20715245
DOI: 10.1002/anie.201002580

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Biocatalysis
Catalytic Domain
Computer Simulation
Ethers / chemistry
Ethers / metabolism
Galactose Oxidase / metabolism*
Oxidation-Reduction
Oxidoreductases / metabolism*
Stereoisomerism

Substances

Ethers
Oxidoreductases
Galactose Oxidase