Osseous metaplasia in a kidney allograft

Nephrol Dial Transplant. 2010 Nov;25(11):3796-8. doi: 10.1093/ndt/gfq490. Epub 2010 Aug 13.

Abstract

Osseous metaplasia is defined by the presence of heterotopic normal bone tissue in a soft tissue. The bone matrix is associated with osteoblasts, osteoclasts, adipocytes and haematopoietic stem cells. Osseous metaplasia pathophysiology is not well known, but many factors have been incriminated including chronic inflammation and chronic ischaemia. We describe the second case of osseous metaplasia in a kidney allograft. Numerous factors might favour its development including factors linked to transplantation failure environment.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Humans
  • Kidney / pathology*
  • Kidney Transplantation / adverse effects*
  • Male
  • Metaplasia
  • Ossification, Heterotopic / pathology*
  • Osteocytes / pathology
  • Transplantation, Homologous