[Optimization of extraction process for compund kaliziran gel with orthogonal design]

Zhongguo Zhong Yao Za Zhi. 2010 May;35(9):1130-3. doi: 10.4268/cjcmm20100909.
[Article in Chinese]

Abstract

Objective: To optimize the extraction process of compund kaliziran gel.

Method: Orthogonal design was used to optimize the extracting process of eight herb medicines with the extract yield, the content of psoralen, isopsoralen and osthole as indexes, and to optimize the extracting process of Polygonum multflorumi and Seman sinapis albae with the extract yield and the content of 2,3,5,4'-tetrehydroxy-stilbene glucoside as indexes.

Result: The optimum extraction progress was as follows:eight herb medicines were extract 2 times for 1 hour with 8 times of 60% alcohol; P. multflorumi and S. sinapis albae were extract 2 times for 1 hour with 8 times of 40% alcohol.

Conclusion: The optimum extraction processes are stable and feasible.

Publication types

  • Evaluation Study

MeSH terms

  • Alcohols / chemistry
  • Chemical Fractionation / methods*
  • Drugs, Chinese Herbal / analysis
  • Drugs, Chinese Herbal / isolation & purification*
  • Plants, Medicinal / chemistry*
  • Technology, Pharmaceutical / methods*

Substances

  • Alcohols
  • Drugs, Chinese Herbal