Pulse-oximetric measurement of prilocaine-induced methemoglobinemia in regional anesthesia

Anesth Analg. 2010 Oct;111(4):1065-8. doi: 10.1213/ANE.0b013e3181eb6239. Epub 2010 Aug 12.

Abstract

Background: The Masimo Radical 7(®) is a new pulse CO oximeter designed to measure methemoglobin. The device has not been evaluated in a clinical setting.

Methods: In this prospective observational study we compared the arterial methemoglobin levels and the corresponding pulse CO-oximetric values of the Radical 7(®) in regional anesthesia with prilocaine.

Results: We analyzed 360 data pairs with methemoglobin values up to 6.6%. The mean bias and limits (± 1.96 sd) of the device were 0.27% (± 1.33%).

Conclusion: We found a high degree of agreement in measurement of methemoglobin between the 2 methods.

Publication types

  • Comparative Study

MeSH terms

  • Anesthesia, Conduction / adverse effects*
  • Humans
  • Methemoglobinemia / chemically induced*
  • Methemoglobinemia / diagnosis*
  • Methemoglobinemia / metabolism
  • Oximetry / instrumentation*
  • Oximetry / methods*
  • Oximetry / standards
  • Prilocaine / adverse effects*
  • Prospective Studies

Substances

  • Prilocaine