Abstract
A syn-enantioselective aldol reaction has been developed using Brønsted acid catalysis based on H(8)-BINOL-derived phosphoric acids. This method affords an efficient synthesis of various beta-hydroxy ketones, some of which could not be synthesized using enamine organocatalysis.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Amanitins / chemistry*
-
Catalysis
-
Combinatorial Chemistry Techniques*
-
Ketones / chemical synthesis*
-
Ketones / chemistry
-
Molecular Structure
-
Phosphoric Acids / chemistry
-
Stereoisomerism
Substances
-
Amanitins
-
Ketones
-
Phosphoric Acids
-
aldoamanitin