Accidental hypothermia: rewarming treatments, complications and outcomes from one university medical centre

Resuscitation. 2010 Nov;81(11):1550-5. doi: 10.1016/j.resuscitation.2010.05.023. Epub 2010 Aug 11.

Abstract

Aim of the study: Accidental hypothermia (AH) is a complex and life threatening condition. Knowledge about epidemiology, rewarming treatments, complications and outcome is limited. This study was initiated to obtain data on causes, rewarming treatments and complications.

Methods: A retrospective cohort study of all patients with a body temperature ≤ 35°C admitted to the Emergency Department (ED) of the VU university medical centre, Amsterdam, The Netherlands, between January 1, 2000 and August 31, 2008. A predefined set of epidemiological and clinical data was retrieved.

Results: Eighty-four patients were included (median age: 47 years). Categories of hypothermia included immersion (18), submersion (29) and exposure to cold (37); concomitant factors were intoxication (26), trauma (40) and homelessness (7). Temperature at admission in the ED was 31.6 ± 2.6°C (mean ± SD), lowest temperature 24.2°C. Fourteen different rewarming treatments were used resulting in a wide range of rewarming speeds. Seventy-nine complications occurred: pulmonary, renal and neurological complications in 20, 17 and 10 patients respectively. Seventeen patients had 2 or more late complications. Twenty-four patients (28.6%) died: 10 during rewarming and 14 after rewarming was completed. Prognosis was poor in older and colder patients and after indoor exposure and submersion.

Conclusion: AH is a rare diagnosis in an inhomogeneous population, treated with a large variety of rewarming techniques. Most complications and death occurred late, after rewarming was completed. Because individual teams gain little clinical experiences, we suggest multiple centre data collection as a first step towards an evidence-based standard of care.

MeSH terms

  • Adult
  • Analysis of Variance
  • Body Temperature
  • Chi-Square Distribution
  • Female
  • Humans
  • Hypothermia / complications*
  • Hypothermia / epidemiology
  • Hypothermia / therapy*
  • Male
  • Middle Aged
  • Netherlands / epidemiology
  • Prognosis
  • Retrospective Studies
  • Rewarming / methods*
  • Risk Factors
  • Statistics, Nonparametric
  • Treatment Outcome