Drug target in eosinophilic meningitis caused by Angiostrongylus cantonensis

Infect Disord Drug Targets. 2010 Oct;10(5):322-8. doi: 10.2174/187152610793180867.

Abstract

Eosinophilic meningitis caused by Angiostrongylus cantonensis is an emerging infectious disease. It is the most common form of human angiostrongyliasis. The diagnosis is made by clinical criteria including the presence of cerebrospinal fluid eosinophils and a history of exposure to A. cantonensis larvae, e.g., from raw freshwater snails or contaminated vegetables. Among various treatment options, corticosteroid is the only effective treatment.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adrenal Cortex Hormones / administration & dosage
  • Angiostrongylus cantonensis / drug effects*
  • Angiostrongylus cantonensis / growth & development
  • Animals
  • Drug Delivery Systems / methods*
  • Eosinophilia / drug therapy*
  • Eosinophilia / etiology
  • Eosinophilia / parasitology*
  • Humans
  • Meningitis / drug therapy*
  • Meningitis / etiology
  • Meningitis / parasitology*
  • Rats
  • Strongylida Infections / complications
  • Strongylida Infections / drug therapy*

Substances

  • Adrenal Cortex Hormones