Isolation of pandamarilactonine-H from the roots of Pandanus amaryllifolius and synthesis of epi-pandamarilactonine-H

J Nat Prod. 2010 Aug 27;73(8):1453-5. doi: 10.1021/np1003998.

Abstract

A new alkaloid (1a), named pandamarilactonine-H, which possesses a methyl-2-(pyrrolidin-2-yl)acetate function, was isolated from the roots of Pandanus amaryllifolius. Eleven known alkaloids were also isolated. Unambiguous assignment of the structure of 1a, including the absolute configuration, was accomplished by spectroscopic analysis and total synthesis of its enantiomer.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkaloids / chemical synthesis
  • Alkaloids / chemistry
  • Alkaloids / isolation & purification*
  • Lactones / chemical synthesis
  • Lactones / chemistry
  • Lactones / isolation & purification*
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Pandanaceae / chemistry*
  • Philippines
  • Plant Roots / chemistry
  • Pyrrolidines / chemical synthesis
  • Pyrrolidines / chemistry
  • Pyrrolidines / isolation & purification*
  • Stereoisomerism

Substances

  • Alkaloids
  • Lactones
  • Pyrrolidines
  • pandamarilactonine-H