Clinicopathological differences between right- and left-sided colonic tumors and impact upon survival

Tech Coloproctol. 2010 Nov:14 Suppl 1:S45-7. doi: 10.1007/s10151-010-0622-z.

Abstract

Aim: This study is to analyze the clinicopathological differences between right- and left-sided colonic tumors and to evaluate the impact upon the patient's survival.

Methods: In a period of 5 years (2004-2009), 453 patients were diagnosed with colorectal cancer.

Results: From a total of 453 patients diagnosed with colon cancer, 56.5% of them were men, while 43.5% of them were women. Right-sided colonic tumors were diagnosed in 54.53% of the patients compared to the 45.47% of patients with left-sided colonic tumors. The size of colonic tumors is statistically significant greater in right-sided colonic tumors compared to left ones (P < 0.001). Left-sided colon cancer patients identified to have a statistically significant better overall 5-year survival rate compared to right-sided ones (P < 0.001).

Conclusion: Based upon our results, there is a different biological profile between right- and left-sided colonic tumors.

MeSH terms

  • Adenocarcinoma / diagnosis
  • Adenocarcinoma / mortality*
  • Adenocarcinoma / pathology*
  • Aged
  • Colonic Neoplasms / diagnosis
  • Colonic Neoplasms / mortality*
  • Colonic Neoplasms / pathology*
  • Colorectal Neoplasms / diagnosis
  • Colorectal Neoplasms / mortality
  • Colorectal Neoplasms / pathology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Retrospective Studies
  • Survival Analysis