Naturally-occurring canine herpesvirus-1 infection of the vestibular labyrinth and ganglion of dogs

Vet J. 2011 Jul;189(1):100-2. doi: 10.1016/j.tvjl.2010.06.014. Epub 2010 Aug 8.

Abstract

Although the involvement of herpesviruses in vestibular disease of humans has been recognised for many years, knowledge of such a link in companion animal species is restricted to cats. This study was conducted to assess the prevalence of canine herpesvirus-1 (CaHV-1) infection of the vestibular labyrinth (VL) and vestibular ganglion (VG) of dogs by PCR. 'Field' herpesvirus was detected in the VL of 17% and in the VG of 19% of 52 dogs, respectively. None of the 11 dogs with infected VG and/or VL exhibited signs of vestibular disease, whereas clinical signs in the remaining three animals were attributable to intra-cranial neoplasia. As reported for other species, the putative role of herpesvirus infection in canine vestibular disease requires further elucidation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • DNA, Viral / analysis
  • Dog Diseases / virology*
  • Dogs
  • Female
  • Ganglia, Sensory / virology*
  • Herpesviridae Infections / epidemiology
  • Herpesviridae Infections / veterinary*
  • Herpesvirus 1, Canid / isolation & purification*
  • Male
  • Polymerase Chain Reaction / veterinary
  • Prevalence
  • Vestibule, Labyrinth / virology*

Substances

  • DNA, Viral