Fibrous cortical defect (nonossifying fibroma) of the mandibular ramus: report of 2 cases

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Oct;110(4):504-8. doi: 10.1016/j.tripleo.2010.04.047. Epub 2010 Aug 6.

Abstract

Fibrous cortical defect, also known as metaphyseal fibrous defect and nonossifying fibroma, among other terms, is a benign, non-neoplastic proliferative process that is relatively common in the long bones of skeletally immature adolescents. Although the lesion is thought to be a developmental abnormality or defect, the exact etiopathogenesis is largely unknown. The lesion has a limited growth potential and good treatment outcome. This process is very rare in the gnathic bones, and only a few sporadic case reports are documented. This article presents the clinicopathologic features of 2 additional cases and reviews the relevant literature in attempt to identify key features and facilitate rendering definitive diagnosis for this rare entity.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Adult
  • Bone Diseases, Developmental / pathology*
  • Diagnosis, Differential
  • Female
  • Fibroblasts / pathology
  • Giant Cells / pathology
  • Humans
  • Male
  • Mandibular Diseases / pathology*