Evasion of natural killer cells by influenza virus

J Leukoc Biol. 2011 Feb;89(2):189-94. doi: 10.1189/jlb.0610319. Epub 2010 Aug 3.

Abstract

NK cells are important innate immune effectors during influenza virus infection. However, the influenza virus seems able to use several tactics to counter NK cell recognition for immune evasion. In this review, we will summarize and discuss recent advances regarding the understanding of NK cell evasion mechanisms manipulated by the influenza virus to facilitate its rapid replication inside the respiratory epithelial cells.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Humans
  • Immune Evasion*
  • Influenza A virus / immunology*
  • Influenza, Human / immunology*
  • Influenza, Human / pathology
  • Influenza, Human / virology*
  • Killer Cells, Natural / immunology*
  • Killer Cells, Natural / pathology