Systemic lupus erythematosus complicated with pulmonary hemorrhage in a 17-year-old female

Lupus. 2010 Nov;19(13):1561-4. doi: 10.1177/0961203310375266. Epub 2010 Aug 3.

Abstract

Pulmonary hemorrhage is a rare and life-threatening complication of systemic lupus erythematosus. In this report, we described a 17-year-old female with pulmonary hemorrhage as an initial manifestation of systemic lupus erythematosus, along with lupus nephritis and central nervous system lupus. High doses of corticosteroids and pulse cyclophosphamide therapy resulted in rapid improvement of respiratory function in our patient.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Cyclophosphamide / administration & dosage
  • Cyclophosphamide / therapeutic use
  • Female
  • Glucocorticoids / administration & dosage
  • Glucocorticoids / therapeutic use
  • Hemorrhage / drug therapy
  • Hemorrhage / etiology*
  • Humans
  • Immunosuppressive Agents / administration & dosage
  • Immunosuppressive Agents / therapeutic use
  • Lung Diseases / drug therapy
  • Lung Diseases / etiology*
  • Lupus Erythematosus, Systemic / complications*
  • Lupus Erythematosus, Systemic / diagnosis
  • Lupus Nephritis / complications
  • Lupus Nephritis / diagnosis
  • Lupus Vasculitis, Central Nervous System / complications
  • Lupus Vasculitis, Central Nervous System / diagnosis
  • Pulse Therapy, Drug

Substances

  • Glucocorticoids
  • Immunosuppressive Agents
  • Cyclophosphamide