Distance measurement between a spin-1/2 and a half-integer quadrupolar nuclei by solid-state NMR using exact analytical expressions

Abstract

We show that the S-RESPDOR NMR method can be used to measure distances between spin-1/2 and half-integer quadrupolar nuclei, and that a general analytical formula describes its dephasing curve for all spin values. We demonstrate the method on the C4-O4 spin pair of L-tyrosine·HCl, with 13C natural abundance and 30% 17O enrichment, using a moderate magnetic field (9.4 T), a moderate 17O rf-field (40 kHz) and a fast spinning speed (22 kHz). It is shown that S-RESPDOR is much more robust and accurate than previous methods.