Comparison of clinical characteristics and neutrophil values in omental infarction and acute appendicitis in children

Pediatr Neonatol. 2010 Jun;51(3):155-9. doi: 10.1016/S1875-9572(10)60029-0.

Abstract

Background: Omental infarction is a rare occurrence in children. It is often diagnosed during surgery for suspected appendicitis. This study investigated the use of clinical and laboratory data for distinguishing between omental infarction and acute appendicitis.

Methods: Seven patients with surgically and pathologically proven omental infarction and 28 age- and sex-matched patients with acute appendicitis were included in this study. The clinical characteristics, imaging study results and laboratory data were analyzed.

Results: All 35 patients had right lower quadrant abdominal pain at presentation. The frequency of nausea and fever were significantly lower in the omental infarction group compared with the acute appendicitis group (p< 0.001 and p= 0.018, respectively). In laboratory studies, the white blood cell count, C-reactive protein value and neutrophil percentage were all higher in the acute appendicitis group compared with the omental infarction group (p= 0.001, p< 0.001, and p= 0.008, respectively). It was possible to separate patients with omental infarction from those with acute appendicitis based on a neutrophil percentage of less than 77% (sensitivity 100%, specificity 100%).

Conclusions: Results of the current study suggest that omental infarction should be considered as a possible diagnosis in patients presenting with right lower quadrant abdominal pain without nausea or fever, and with a neutrophil percentage below 77%.

Publication types

  • Comparative Study

MeSH terms

  • Abdomen, Acute / blood
  • Abdomen, Acute / diagnosis*
  • Appendectomy
  • Appendicitis / blood
  • Appendicitis / diagnosis*
  • Appendicitis / surgery
  • Biomarkers / blood
  • C-Reactive Protein / metabolism
  • Case-Control Studies
  • Chi-Square Distribution
  • Child
  • Diagnosis, Differential
  • Humans
  • Infarction / blood
  • Infarction / diagnosis*
  • Leukocyte Count
  • Neutrophils*
  • Omentum / blood supply*
  • ROC Curve
  • Sensitivity and Specificity

Substances

  • Biomarkers
  • C-Reactive Protein