Objective: To investigate specific immunologic therapy (SIT) intervention in patients with nasal polyps accompanied with perennial rhinitis after functional endoscopic sinus surgery (FESS).
Method: To divide patients with nasal polyps into two groups randomly: group I: FESS + SIT after operation; group II: FESS only. To compare the symptom and physical sign of the 2 groups before the operation and 1 and 2 years after the operation, with SNOT-20 and Lund-Kennedy and Lund-Mackay Standard.
Result: Both of the 2 groups' final scores of the total 20 items and the most important 5 items of SNOT-20 and Lund-Kennedy and Lund-Mackay were greatly improved, however there is an obvious difference between them: the therapeutic effect of groups I is better than group II.
Conclusion: SIT can reduce the recurrence of nasal polyps after operation, and improve the state after treatment.