Tuning the cis/trans conformer ratio of Xaa-Pro amide bonds by intramolecular hydrogen bonds: the effect on PPII helix stability

Angew Chem Int Ed Engl. 2010 Aug 23;49(36):6324-7. doi: 10.1002/anie.201001851.

Authors

Michael Kuemin¹, Yvonne A Nagel, Sabine Schweizer, Fabien W Monnard, Christian Ochsenfeld, Helma Wennemers

Affiliation

¹ Department of Chemistry, University of Basel, St. Johanns-Ring 19, 4056 Basel, Switzerland.

PMID: 20665611
DOI: 10.1002/anie.201001851

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amides / chemistry*
Dipeptides / chemistry*
Hydrogen Bonding
Isomerism
Proline / chemistry
Protein Structure, Secondary
Thermodynamics

Substances

Amides
Dipeptides
Proline