Unsupervised skin lesions border detection via two-dimensional image analysis

Comput Methods Programs Biomed. 2011 Dec;104(3):e1-15. doi: 10.1016/j.cmpb.2010.06.016. Epub 2010 Jul 21.

Abstract

The skin cancer was analyzed by dermoscopy helpful for dermatologists. The classification of melanoma and carcinoma such as basal cell, squamous cell, and merkel cell carcinomas tumors can be increased the sensitivity and specificity. The detection of an automated border is an important step for the correctness of subsequent phases in the computerized melanoma recognition systems. The artifacts such as, dermoscopy-gel, specular reflection and outline (skin lines, blood vessels, and hair or ruler markings) were also contained in the dermoscopic images. In this paper, we present an unsupervised approach for multiple lesion segmentation, modification of Region-based Active Contours (RACs) as well as artifact diminution steps. Iterative thresholding is applied to initialize level set automatically; the stability of curves is enforced by maximum smoothing constraints on Courant-Friedreichs-Lewy (CFL) function. The work has been tested on dermoscopic database of 320 images. The border detection error is quantified by five distinct statistical metrics and manually used to determine the borders from a dermatologist as the ground truth. The segmentation results were compared with other state-of-the-art methods along with the evaluation criteria. The unsupervised border detection system increased the true detection rate (TDR) is 4.31% and reduced the false positive rate (FPR) of 5.28%.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carcinoma, Basal Cell / diagnosis*
  • Carcinoma, Basal Cell / pathology
  • Carcinoma, Merkel Cell / diagnosis*
  • Carcinoma, Merkel Cell / pathology
  • Carcinoma, Squamous Cell / diagnosis*
  • Carcinoma, Squamous Cell / pathology
  • Humans
  • Melanoma / diagnosis*
  • Melanoma / pathology
  • Sensitivity and Specificity
  • Skin Neoplasms / diagnosis*
  • Skin Neoplasms / pathology