Research has shown that an individual's implicit power motive relates to 2 types of behavioral clusters: either prosocial, socially appropriate behaviors or profligate, impulsive behaviors. The present study examined the relationship between individuals' implicit power motives and their tendency to engage in sexual activities without strong emotional ties (i.e., sociosexuality). For men, but not for women, this relationship was hypothesized to be moderated by an implicit disposition for responsibility. Whereas most research has been limited to Euro-American contexts, the present study examined the relationship between power motive, disposition for responsibility, and sociosexuality among participants recruited in Cameroon, China, Costa Rica, and Germany. Explicit Big Five measures of personality were controlled for. For women, only a main effect of responsibility on sociosexuality was found across cultural groups; for men, the association between power motivation and sociosexuality was moderated by responsibility, independent of cultural group. Traits of agreeableness and conscientiousness were systematically related to lower levels of sociosexuality. Effects for both implicit and explicit measures of personality suggest universality in the processes associated with more enactments of sociosexuality, confirming in part the hypothesized role of responsibility in channeling the realization of the power motive into less impulsive activities. (PsycINFO Database Record (c) 2010 APA, all rights reserved).