Abstract
Chronic meningococcaemia is an unusual clinical presentation of Neisseria meningitidis infection. We describe the case of a patient, who presented with total IgA deficiency and partial IgM deficiency with a low switched memory B cells count, suggestive of a borderline form of common variable immunodeficiency (CVID). The role of IgA in the protection against Neisseria meningitidis, and the link between IgA deficiency and CVID are discussed.
MeSH terms
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Bacteremia / complications*
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Bacteremia / diagnosis*
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Bacteremia / microbiology
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Common Variable Immunodeficiency / complications*
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Common Variable Immunodeficiency / diagnosis*
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Exanthema / etiology
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Exanthema / pathology
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Female
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Humans
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Immunoglobulin A / immunology
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Meningococcal Infections / complications*
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Meningococcal Infections / diagnosis*
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Meningococcal Infections / microbiology
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Neisseria meningitidis / isolation & purification*
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Young Adult