This paper describes a novel healthcare IT platform developed under the LOBIN project, which allows monitoring several physiological parameters, such as ECG, heart rate, body temperature, etc., and tracking the location of a group of patients within hospital environments. The combination of e-textile and wireless sensor networks provides an efficient way to support noninvasive and pervasive services demanded by future healthcare environments. This paper presents the architecture, system deployment as well as validation results from both laboratory tests and a pilot scheme developed with real users in collaboration with the Cardiology Unit at La Paz Hospital, Madrid, Spain.