Genetic variability of 15 autosomal STR loci in Russian populations

Vadim A Stepanov; Alexander V Melnikov; Andrey Yu Lash-Zavada; Vladimir N Kharkov; Svetlana A Borinskaya; Tatiana V Tyazhelova; Olga V Zhukova; Yuri V Schneider; Irina N Shil'nikova; Valery P Puzyrev; Anna A Rybakova; Nikolai K Yankovsky

doi:10.1016/j.legalmed.2010.05.006

Genetic variability of 15 autosomal STR loci in Russian populations

Leg Med (Tokyo). 2010 Sep;12(5):256-8. doi: 10.1016/j.legalmed.2010.05.006. Epub 2010 Jul 13.

Authors

Vadim A Stepanov¹, Alexander V Melnikov, Andrey Yu Lash-Zavada, Vladimir N Kharkov, Svetlana A Borinskaya, Tatiana V Tyazhelova, Olga V Zhukova, Yuri V Schneider, Irina N Shil'nikova, Valery P Puzyrev, Anna A Rybakova, Nikolai K Yankovsky

Affiliation

¹ Institute for Medical Genetics, Russian Academy of Medical Sciences, Nab. Ushayky 10, 634050, Tomsk, Russia. vadim.stepanov@medgenetics.ru

PMID: 20630785
DOI: 10.1016/j.legalmed.2010.05.006

Abstract

Allele frequencies for 15 STRs (CSF1PO, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D21S11, FGA, Penta D, Penta E, THO1, TPOX, and vWA) in the PowerPlex 16 System (Promega Corporation) were assessed in 386 individuals from five Russian urban populations. No significant between-population differences in frequencies and molecular variance of 15 microsatellites were revealed. For all 15 loci, the combined matching probability is 3.19 x 10(-18) and the power of exclusion is 99.99989%.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alleles
Forensic Genetics
Gene Frequency
Genetic Variation*
Genetics, Population*
Humans
Polymerase Chain Reaction
Polymorphism, Genetic
Russia
Tandem Repeat Sequences / genetics*
White People / genetics*