Abstract
We report the case of a young man with chronic hepatitis B infection of probable perinatal acquisition who was diagnosed with hepatocellular carcinoma at a very early stage (BCLC 0) with a highly favorable prognosis. However, the tumor progressed rapidly and the patient died within months. Currently, there are few data that could help to identify cases likely to show rapid progression and which could prompt initiation of aggressive therapies that might prevent or control such progression.
Copyright © 2010 Elsevier España, S.L. All rights reserved.
MeSH terms
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Adult
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Antiviral Agents / therapeutic use
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Biomarkers, Tumor / blood
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Carcinoma, Hepatocellular / diagnostic imaging
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Carcinoma, Hepatocellular / etiology
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Carcinoma, Hepatocellular / pathology*
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Carcinoma, Hepatocellular / surgery
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Carcinoma, Hepatocellular / therapy
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Chemoembolization, Therapeutic
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Combined Modality Therapy
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Disease Progression
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Doxorubicin / administration & dosage
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Fatal Outcome
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Hepatectomy* / methods
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Hepatitis B, Chronic / complications
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Hepatitis B, Chronic / congenital
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Hepatitis B, Chronic / virology
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Humans
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Interferons / therapeutic use
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Lamivudine / therapeutic use
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Liver Neoplasms / diagnostic imaging
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Liver Neoplasms / etiology
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Liver Neoplasms / pathology*
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Liver Neoplasms / surgery
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Liver Neoplasms / therapy
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Magnetic Resonance Imaging
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Male
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Ultrasonography
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Viral Load
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alpha-Fetoproteins / analysis
Substances
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Antiviral Agents
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Biomarkers, Tumor
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alpha-Fetoproteins
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Lamivudine
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Doxorubicin
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Interferons