[Research traditional Chinese medicine properties by detecting rats' monoamine neurotransmitter after given two different traditional Chinese medicine]

Zhongguo Zhong Yao Za Zhi. 2010 Apr;35(8):1022-4.
[Article in Chinese]

Abstract

Objective: To find out the essence of the traditional Chinese medicine properties from detecting the rats' monoamine neurotransmitter after given different traditional Chinese drug.

Method: The property of rhizome curcumae and radix curcumae is opposite, they were given to rats respectively for one month. Next, HPLC-ECD method was used to detect the rats' monoamine neurotransmitter in different encephalic region.

Result: Rhizome curcumae can raise the rats' monoamine neurotransmitter, but radix curcumae inhibits the rats' monoamine neurotransmitter.

Conclusion: There are correlations between the traditional Chinese medicine properties and monoamine neurotransmitter.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Biogenic Monoamines / metabolism*
  • Brain / drug effects*
  • Brain / metabolism*
  • Chromatography, High Pressure Liquid
  • Curcuma / chemistry*
  • Drugs, Chinese Herbal / pharmacology*
  • Male
  • Neurotransmitter Agents / metabolism*
  • Rats
  • Rats, Wistar

Substances

  • Biogenic Monoamines
  • Drugs, Chinese Herbal
  • Neurotransmitter Agents