Identification of undiagnosed type 2 diabetes by systolic blood pressure and waist-to-hip ratio

Diabetologia. 2010 Oct;53(10):2139-46. doi: 10.1007/s00125-010-1841-6. Epub 2010 Jul 2.

Abstract

Aims/hypothesis: We estimated the current prevalence of type 2 diabetes in the Vietnamese population and developed simple diagnostic models for identifying individuals at high risk of undiagnosed type 2 diabetes.

Methods: The study was designed as a cross-sectional investigation with 721 men and 1,421 women, who were aged between 30 and 72 years and were randomly sampled from Ho Chi Minh City (formerly Saigon) in Vietnam. A 75 g oral glucose tolerance test to assess fasting and 2 h plasma glucose concentrations were determined for each individual. The ADA diagnostic criteria were used to determine the prevalence of type 2 diabetes. WHR and blood pressure were also measured in all individuals.

Results: The prevalence of type 2 diabetes was 10.8% in men and 11.7% in women. Higher WHR and blood pressure were independently associated with a greater risk of type 2 diabetes. Compared with participants without central obesity and hypertension, the odds of diabetes was increased by 6.4-fold (95% CI 3.2-13.0) in men and 4.1-fold (2.2-7.6) in women with central obesity and hypertension. Two nomograms were developed that help identify men and women at high risk of type 2 diabetes.

Conclusions/interpretation: The current prevalence of type 2 diabetes in the Vietnamese population is high. Simple field measurements such as waist-to-hip ratio and systolic blood pressure can identify individuals at high risk of undiagnosed type 2 diabetes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Blood Glucose / analysis
  • Blood Pressure / physiology*
  • Cross-Sectional Studies
  • Diabetes Mellitus, Type 2 / diagnosis*
  • Diabetes Mellitus, Type 2 / epidemiology*
  • Diabetes Mellitus, Type 2 / physiopathology
  • Female
  • Glucose Tolerance Test
  • Humans
  • Hypertension / epidemiology
  • Male
  • Middle Aged
  • Prevalence
  • ROC Curve
  • Risk Factors
  • Sex Factors
  • Vietnam / epidemiology
  • Waist-Hip Ratio*

Substances

  • Blood Glucose