One-pot synthesis of azaindoles via palladium-catalyzed alpha-heteroarylation of ketone enolates

J Org Chem. 2010 Aug 6;75(15):5316-9. doi: 10.1021/jo100623d.

Abstract

A convenient, one-pot method for the construction of a variety of azaindoles using simple ketones and haloaminopyridines is described.

MeSH terms

  • Aza Compounds / chemical synthesis*
  • Catalysis
  • Indoles / chemical synthesis*
  • Ketones / chemistry*
  • Magnetic Resonance Spectroscopy
  • Mass Spectrometry
  • Palladium / chemistry*

Substances

  • Aza Compounds
  • Indoles
  • Ketones
  • Palladium