Given the Canadian Aboriginal People's colonial legacy of multiple deprivations, the discord between an Aboriginal worldview and the dominant neo-liberal culture in Canada, and the recognized disadvantage vulnerability of single mothers, this quantitative study was aimed at increasing the understanding of exclusion, specifically with reference to the domains of disadvantage of Saskatchewan Aboriginal/Non-Aboriginal single mothers. We conducted a self-administered survey (random selection) of Saskatchewan single mothers (ages 18-59) who had at least one child less than 18 years of age living with them. In our cross-sectional self-administered survey, we compared specific social aspects of life between groups of randomly selected Saskatchewan single mothers, Aboriginal and Non-Aboriginal. An exploratory factor analysis identified two factors identified as domains of disadvantage loaded in excess of .30. These two factors accounted for 43% of the common variance in the Aboriginal sample and 47% in the Non-Aboriginal one. What was especially noteworthy was the striking similarity of how these variables tend to cluster together in the two distinct groups from which they were derived. This research will hopefully lead to further studies which endeavor to determine whether such initiatives aimed at enhancing the levels of social inclusion of those regarded as disadvantaged ultimately also impacts their health and well being. Further studies of this nature would help to clarify whether or not the relationship among these measures of adjustment is causal.