Abstract
The bis-THF cores of annonaceous acetogenins were synthesized using (3R,4R)-1,5-hexadiene-3,4-diol (1) as the sole source of carbon atoms. The methylene acetal function was applied as a new linker/tether to facilitate the ring-closing metathesis.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acetogenins / chemistry*
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Cross-Linking Reagents / chemistry
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Furans / chemical synthesis*
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Molecular Structure
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Stereoisomerism
Substances
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Acetogenins
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Cross-Linking Reagents
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Furans
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tetrahydrofuran