Abstract
Detection of the bla(VIM-12) gene within the originally described Inh12 integron in a clinical isolate of Enterobacter cloacae is reported for the first time worldwide. Integron Inh12 was carried on a conjugative plasmid of approximately 85 kb which also conferred resistance to aztreonam, likely due to AmpC production.
MeSH terms
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Anti-Bacterial Agents / pharmacology
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Enterobacter cloacae / drug effects*
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Enterobacter cloacae / enzymology*
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Enterobacter cloacae / genetics
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Enterobacter cloacae / isolation & purification
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Enterobacteriaceae Infections / microbiology*
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Humans
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Integrons
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Microbial Sensitivity Tests
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Plasmids / analysis
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beta-Lactam Resistance*
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beta-Lactamases / biosynthesis
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beta-Lactamases / genetics*
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beta-Lactams / pharmacology
Substances
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Anti-Bacterial Agents
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beta-Lactams
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beta-Lactamases