Topical treatment of psoriasis

Expert Opin Pharmacother. 2010 Aug;11(12):1999-2009. doi: 10.1517/14656566.2010.492778.

Abstract

Importance of the field: The majority of patients with psoriasis can be safely and effectively treated with topical therapy alone, either under the supervision of a family physician or dermatologist. For those requiring systemic agents, topical therapies can provide additional benefit. Optimal use of topical therapy requires an awareness of the range and efficacy of all products.

Areas covered in this review: The review covers the efficacy and role of topical therapies including emollients, corticosteroids, vitamin D analogs, calcineurin inhibitors, dithranol, coal tar, retinoids, keratolyics and combination therapy. The report was prepared following a PubMed and Embase literature search up to April 2010.

What the reader will gain: The paper provides a broad review of the relevant topical therapeutic options available in routine clinical practice for the management of psoriasis and a recommendation for selection of treatment.

Take home message: Topical therapies used appropriately provide a safe and effective option for the management of psoriasis. An awareness of the available products and their efficacy is key to treatment selection and patient satisfaction.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Administration, Topical
  • Dermatologic Agents / administration & dosage*
  • Dermatologic Agents / adverse effects
  • Humans
  • Patient Selection
  • Practice Guidelines as Topic
  • Psoriasis / drug therapy*
  • Risk Assessment
  • Treatment Outcome

Substances

  • Dermatologic Agents