Preliminary crystallographic analysis of cardiotoxin V with major fusion activity from Taiwan cobra (Naja naja atra) venom

C J Chen; J Rose; C D Hsiao; T J Lee; W G Wu; B C Wang

doi:10.1016/0022-2836(91)90653-n

Preliminary crystallographic analysis of cardiotoxin V with major fusion activity from Taiwan cobra (Naja naja atra) venom

J Mol Biol. 1991 Jun 20;219(4):591-2. doi: 10.1016/0022-2836(91)90653-n.

Authors

C J Chen¹, J Rose, C D Hsiao, T J Lee, W G Wu, B C Wang

Affiliation

¹ Department of Crystallography, University of Pittsburgh, PA 15260.

PMID: 2056526
DOI: 10.1016/0022-2836(91)90653-n

Abstract

Crystals of a cardiotoxin from Taiwan cobra venom have been obtained by the vapor diffusion method using methyl pentanediol as precipitant. The crystals belong to the hexagonal space group P6(1)22 (or P6(5)22), with cell dimensions a = b = 47.5 A, c = 111.3 A, alpha = beta = 90 degrees and gamma = 120 degrees and diffract to a resolution of 2.2 A. There is one molecule per asymmetric unit and the solvent content is estimated to be 53%.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cobra Cardiotoxin Proteins / chemistry*
Cobra Cardiotoxin Proteins / toxicity
Crystallization
Molecular Structure
X-Ray Diffraction

Substances

Cobra Cardiotoxin Proteins