Fulminant pancytopenia due to cytomegalovirus infection in an immunocompetent adult

Braz J Infect Dis. 2010 Mar-Apr;14(2):180-2.

Abstract

A case of severe and irreversible pancytopenia secondary to acute primary cytomegalovirus infection in an immunocompetent woman is described. The patient presented with thrombocytopenia, lymphopenia, anemia, and abnormal liver function tests. Treatment with corticosteroids and intravenous immunoglobulin was ineffective in reconstituting hemopoiesis. The patient developed severe sepsis and eventually expired.

Publication types

  • Case Reports

MeSH terms

  • Cytomegalovirus Infections / complications*
  • Cytomegalovirus Infections / diagnosis
  • Cytomegalovirus Infections / drug therapy
  • Fatal Outcome
  • Female
  • Glucocorticoids / therapeutic use
  • Humans
  • Immunocompetence*
  • Immunoglobulins, Intravenous / therapeutic use
  • Middle Aged
  • Pancytopenia / drug therapy
  • Pancytopenia / etiology*
  • Prednisolone / therapeutic use
  • Sepsis / etiology*
  • Severity of Illness Index

Substances

  • Glucocorticoids
  • Immunoglobulins, Intravenous
  • Prednisolone