Comorbid chronic diseases in depressed and non-depressed patients in family practice

Psychiatr Danub. 2010 Jun;22(2):236-40.

Abstract

Introduction: Depression is one of the five most frequent disorders in primary care practice and often remains unrecognized. One of the reasons why depression often passes unnoticed is comorbidity - a number of different chronic diseases coexist with depression, especially in elderly patients.

Aim: The aim of this research was to assess the difference between depressed and non-depressed patients regarding somatic and mental comorbidity. The differences in drug use were also examined.

Subjects and methods: Five hundred successive adult patients visiting family physicians in Rijeka, Croatia, were polled using the Beck Depression Inventory and a general questionnaire which was created for the purpose of the study. The existing medical records were also used.

Results: Elevated depression level was determined in 48.1% of the examinees. These patients were suffering from larger number of chronic diseases (X=1.23) than non-depressed patients (X=0.70; t=5.07; p<0.001; z=4.93; p<0.001), especially cardiac, mental, renal and osteomuscular diseases. Depressed persons used significantly more drugs (X=1.28) than non-depressed patients (X=0.58; t=6.10; p<0.001; z=5.78; p<0.001), especially antirheumatics, analgesics, sedatives, antidepressants, antiallergics and diuretics.

Conclusion: The research results point to a necessity of routine screening and early treatment of depression in patients with chronic diseases in primary care practice.

MeSH terms

  • Adult
  • Aged
  • Antidepressive Agents / therapeutic use
  • Chronic Disease / epidemiology*
  • Chronic Disease / psychology
  • Chronic Disease / therapy
  • Comorbidity
  • Croatia
  • Depressive Disorder / diagnosis
  • Depressive Disorder / drug therapy
  • Depressive Disorder / epidemiology*
  • Depressive Disorder / psychology
  • Drug Therapy, Combination
  • Drug Utilization / statistics & numerical data
  • Family Practice
  • Female
  • Health Surveys
  • Humans
  • Male
  • Mass Screening / statistics & numerical data
  • Middle Aged
  • Personality Inventory / statistics & numerical data
  • Psychometrics

Substances

  • Antidepressive Agents