Implantable device therapy for the treatment of resistant hypertension

J Cardiovasc Transl Res. 2009 Jun;2(2):150-3. doi: 10.1007/s12265-009-9093-x. Epub 2009 Mar 4.

Abstract

The prevalence of resistant hypertension continues to increase and the standard approaches of therapeutic lifestyle changes and drug therapy are ineffective in bringing many of these patients to goal blood pressure. Electrical stimulation of the carotid sinus baroreceptor through a surgically implanted device is presently under clinical investigation and is showing some encouraging early results. This review discusses the evolution of this therapy including a review of the current data available from the early stages of ongoing clinical trials.

Publication types

  • Review

MeSH terms

  • Animals
  • Antihypertensive Agents / therapeutic use*
  • Baroreflex*
  • Blood Pressure
  • Clinical Trials as Topic
  • Drug Resistance*
  • Electric Stimulation Therapy / instrumentation*
  • Electrodes, Implanted
  • Equipment Design
  • Evidence-Based Medicine
  • Humans
  • Hypertension / drug therapy
  • Hypertension / physiopathology
  • Hypertension / therapy*
  • Pressoreceptors / physiopathology*
  • Treatment Failure

Substances

  • Antihypertensive Agents