'Turning the right screw': targeting the interleukin-6 receptor to reduce unfavourable tissue remodelling after myocardial infarction

Cardiovasc Res. 2010 Aug 1;87(3):395-6. doi: 10.1093/cvr/cvq186. Epub 2010 Jun 16.
No abstract available

Publication types

  • Editorial
  • Comment

MeSH terms

  • Animals
  • Antibodies, Neutralizing / administration & dosage
  • Antibodies, Neutralizing / pharmacology*
  • Chemokine CCL2 / metabolism
  • Fibrosis
  • Injections, Intraperitoneal
  • Interleukin-6 / metabolism
  • Macrophages / drug effects
  • Macrophages / immunology
  • Matrix Metalloproteinase 2 / metabolism
  • Mice
  • Myocardial Infarction / diagnostic imaging
  • Myocardial Infarction / drug therapy*
  • Myocardial Infarction / immunology
  • Myocardial Infarction / physiopathology
  • Myocardium / immunology*
  • Myocardium / metabolism
  • Myocardium / pathology
  • Neutrophil Infiltration / drug effects
  • Peroxidase / metabolism
  • Receptors, Interleukin-6 / antagonists & inhibitors*
  • Receptors, Interleukin-6 / immunology
  • Ultrasonography
  • Ventricular Remodeling / drug effects*

Substances

  • Antibodies, Neutralizing
  • Ccl2 protein, mouse
  • Chemokine CCL2
  • Interleukin-6
  • Receptors, Interleukin-6
  • Peroxidase
  • Matrix Metalloproteinase 2
  • Mmp2 protein, mouse