Type III hypersensitivity to insulin leading to leukocytoclastic vasculitis

B Rachid; M Rabelo-Santos; E Mansour; R de Lima Zollner; L A Velloso

doi:10.1016/j.diabres.2010.05.019

Type III hypersensitivity to insulin leading to leukocytoclastic vasculitis

Diabetes Res Clin Pract. 2010 Sep;89(3):e39-40. doi: 10.1016/j.diabres.2010.05.019. Epub 2010 Jun 16.

Authors

B Rachid¹, M Rabelo-Santos, E Mansour, R de Lima Zollner, L A Velloso

Affiliation

¹ Clinical Immunology, Department of Internal Medicine, University of Campinas, DCM - FCM Unicamp, 13083-970 Campinas, SP, Brazil.

PMID: 20557967
DOI: 10.1016/j.diabres.2010.05.019

Abstract

Here, we report the occurrence of leukocytoclastic vasculitis as an outcome of type III allergy to insulin in a patient with type II diabetes mellitus. The diagnosis was made on the basis of anatomo-pathological examination of a skin biopsy.

Publication types

Case Reports

MeSH terms

Adult
Diabetes Mellitus, Type 2 / complications
Diabetes Mellitus, Type 2 / immunology
Humans
Hypersensitivity / complications*
Immune Complex Diseases / complications*
Insulin / immunology*
Male
Vasculitis, Leukocytoclastic, Cutaneous / diagnosis*
Vasculitis, Leukocytoclastic, Cutaneous / etiology*

Substances

Insulin