Effectiveness of high-dose barium enema filling for colonic diverticular bleeding

Colorectal Dis. 2011 Aug;13(8):896-8. doi: 10.1111/j.1463-1318.2010.02350.x. Epub 2010 Jun 10.

Abstract

Aim: Therapeutic barium enema was first reported in 1970. The long-term recurrence rate of colonic diverticular bleeding after therapeutic barium enema was compared with that of endoscopic haemostasis.

Method: This study included 57 consecutive patients admitted between 2003 and 2008 with colonic diverticular bleeding in whom conservative treatment failed to stop bleeding within 3 h of hospital admission. Lower gastrointestinal endoscopy was performed immediately after admission. In 75% of patients, bleeding was from the right colon, and any identifiable source of bleeding was treated by endoscopic haemostasis. Cases with an undetectable source received high-dose barium impaction therapy.

Results: Treatment was as follows: Group A (n = 37) solely by endoscopic haemostasis; Group B (n = 11) solely by therapeutic barium enema group, and Group C (n = 9) by endoscopic haemostasis and therapeutic barium enema. At a follow up of seven (median; range: 1-56) months, recurrent bleeding rates were 18/37 (48.6%), 6/11 (54.5%) and 2/9 (22.2%) (P = 0.3930).

Conclusion: High-dose barium enema is as effective as endoscopic haemostasis for the prevention of recurrent diverticular bleeding.

Publication types

  • Comparative Study
  • Controlled Clinical Trial

MeSH terms

  • Aged
  • Barium Sulfate / administration & dosage*
  • Colonic Diseases / complications*
  • Colonic Diseases / therapy
  • Diverticulum, Colon / complications*
  • Diverticulum, Colon / therapy
  • Enema*
  • Female
  • Gastrointestinal Hemorrhage / etiology
  • Gastrointestinal Hemorrhage / prevention & control*
  • Gastrointestinal Hemorrhage / therapy
  • Hemostasis, Endoscopic*
  • Humans
  • Kaplan-Meier Estimate
  • Male
  • Middle Aged
  • Recurrence

Substances

  • Barium Sulfate