[Dihydroflavones in Rhododendron concinnum]

Zhongguo Zhong Yao Za Zhi. 2010 Mar;35(6):722-4. doi: 10.4268/cjcmm20100614.
[Article in Chinese]

Abstract

Objective: To study the chemical constituents of the whole plant of Rhododendron concinnum.

Method: The compounds were isolated and purified by chromatography on silica gel and polyamide. Their structures were identified on the basis of spectroscopic data (MS,1H-NMR and 13C-NMR) and chemical evidence.

Result: Five dihydroflavones were isolated and identified as (2R)-farrerol-7-O-glucopyranoside (1), (2R,3R)-(-)-dihydroquercetin-3-O-beta-D-xylopyranoside(2), (2S,3S)-(-)-dihydroquercetin-3-O-beta-D-glucopyranoside(3), eriodictyol-7-O-beta-D-glucopyranoside (4) , (2R, 3R)-(+)-dihydroquercetin (5).

Conclusion: Except compound 5, others were firstly isolated from the genus Rhododendron.

Publication types

  • English Abstract

MeSH terms

  • Antineoplastic Agents, Phytogenic / pharmacology*
  • Cell Line, Tumor
  • Cell Survival / drug effects*
  • Chromatography, High Pressure Liquid / methods
  • Chromones / chemistry
  • Humans
  • Inhibitory Concentration 50
  • Magnetic Resonance Spectroscopy
  • Quercetin / analogs & derivatives*
  • Quercetin / analysis
  • Quercetin / pharmacology
  • Rhododendron / chemistry*
  • Silica Gel
  • Silicon Dioxide / analysis
  • Silicon Dioxide / pharmacology

Substances

  • Antineoplastic Agents, Phytogenic
  • Chromones
  • farrerol
  • Silica Gel
  • Silicon Dioxide
  • Quercetin
  • taxifolin