Diketopiperazines produced by endophytic fungi found in association with two Asteraceae species

Denise O Guimarães; Warley S Borges; Noemi J Vieira; Laiani F de Oliveira; Carlos H T P da Silva; Norberto P Lopes; Luis G Dias; Rosa Durán-Patrón; Isidro G Collado; Mônica T Pupo

doi:10.1016/j.phytochem.2010.05.012

Diketopiperazines produced by endophytic fungi found in association with two Asteraceae species

Phytochemistry. 2010 Aug;71(11-12):1423-9. doi: 10.1016/j.phytochem.2010.05.012. Epub 2010 Jun 10.

Authors

Denise O Guimarães¹, Warley S Borges, Noemi J Vieira, Laiani F de Oliveira, Carlos H T P da Silva, Norberto P Lopes, Luis G Dias, Rosa Durán-Patrón, Isidro G Collado, Mônica T Pupo

Affiliation

¹ Departamento de Ciências Farmacêuticas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Avenida do Café s/n, 14040-903 Ribeirão Preto, SP, Brazil.

PMID: 20541231
DOI: 10.1016/j.phytochem.2010.05.012

Abstract

Diketopiperazine (DKP) derivatives, named colletopiperazine, fusaperazine C and E as well as four known DKPs were isolated from cultures of Colletotrichum gloeosporioides, Penicillium crustosum, both endophytic fungi isolated from Viguiera robusta, and a Fusarium spp., an endophyte of Viguiera arenaria, respectively. Their structures were established on the basis of their spectroscopic data. Conformational analysis of two known DKPs showed that folded conformations were as energetically stable as the extended one.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Asteraceae / classification
Asteraceae / microbiology*
Colletotrichum / chemistry
Diketopiperazines / chemistry
Diketopiperazines / isolation & purification*
Fungi / chemistry
Fungi / isolation & purification*
Fusarium / chemistry
Molecular Conformation
Molecular Structure
Nuclear Magnetic Resonance, Biomolecular
Penicillium / chemistry

Substances

Diketopiperazines