Importance of renal mass on graft function outcome after 12 months of cadaveric donor kidney transplantation

Transplant Proc. 2010 May;42(4):1093-4. doi: 10.1016/j.transproceed.2010.03.121.

Abstract

Background: Few studies have measured cadaveric kidney weight to investigate its relation to recipient kidney function related to it. The aim of this study was to evaluate kidney weight (cadaveric donor) and its relationship to creatinine clearance (CrCl) after 12 months posttransplantation.

Methods: We evaluated 81 renal transplantation recipients from cadaveric donors. We collected donor and recipient demographic, clinical and anthropometric data. Data about kidney weight were obtained through kidney measurement using an electronic machine at the moment of transplantation.

Results: The mean kidney weight was 201.4 +/- 10.2 g (200.5 +/- 11.6 g in women and 210.3 +/- 14.1 g in men). Kidney weight correlated with CrCl at 12 months (0.001). The CrCl at 12 months showed a significant correlation of graft weight/recipient weight ratio (P < .01).

Conclusion: The cadaveric donor kidney weight significantly influenced the CrCl at 12 months after transplantation.

MeSH terms

  • Adult
  • Aged
  • Body Mass Index
  • Cadaver
  • Creatinine / blood
  • Female
  • Humans
  • Kidney / anatomy & histology*
  • Kidney Transplantation / physiology*
  • Male
  • Middle Aged
  • Nephrons / physiology
  • Organ Size
  • Tissue Donors
  • Treatment Outcome

Substances

  • Creatinine