Multicomponent, home-based resistance training for obese adults with type 2 diabetes: a randomized controlled trial

Int J Obes (Lond). 2010 Dec;34(12):1733-41. doi: 10.1038/ijo.2010.109. Epub 2010 Jun 8.

Abstract

Purpose: To investigate whether a home-based resistance training (RT) program that supplied high-quality equipment and qualified exercise specialists could provide benefits to obese patients with type 2 diabetes.

Methods: A total of 48 obese individuals with type 2 diabetes were randomly assigned to either an RT (n=27) or a control group (n=21). Those in the RT group received a multigym and dumbbells and performed RT 3 days per week for 16 weeks at home. A qualified exercise specialist supervised training, with supervision being gradually decreased throughout the study. Primary outcome measures included strength and hemoglobin-A1C, whereas secondary outcome measures included other cardiovascular risk markers, key social-cognitive constructs and health-related quality of life.

Results: Intention-to-treat analyses indicated a significant increase in upper and lower body strength for the RT group compared with controls (20-37% mean increases in the RT group). No significant reduction in A1C levels was observed. The RT group had unchanged high-density lipoprotein cholesterol levels in comparison to declines in the control group. Significant reductions in fasting insulin, and increases in RT-related self-efficacy and intentions, were also observed in the RT group.

Conclusions: Supervised home-based RT with high-quality equipment was effective for improving strength, along with other secondary outcomes in obese patients with type 2 diabetes.

Trial registration: ClinicalTrials.gov NCT00221208.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Blood Glucose / metabolism*
  • Body Composition
  • Body Mass Index
  • Canada
  • Diabetes Mellitus, Type 2 / blood*
  • Diabetes Mellitus, Type 2 / physiopathology
  • Diabetes Mellitus, Type 2 / rehabilitation
  • Female
  • Glycated Hemoglobin / metabolism
  • Health Status
  • Home Care Services / standards
  • Humans
  • Male
  • Middle Aged
  • Muscle Strength / physiology
  • Muscle, Skeletal / metabolism*
  • Muscle, Skeletal / physiopathology
  • Obesity / blood*
  • Obesity / physiopathology
  • Obesity / rehabilitation
  • Patient Compliance
  • Prospective Studies
  • Quality of Life
  • Resistance Training / methods*
  • Treatment Outcome

Substances

  • Blood Glucose
  • Glycated Hemoglobin A

Associated data

  • ClinicalTrials.gov/NCT00221208