Pineal anlage tumor in a 5-month-old boy

J Neurosurg Pediatr. 2010 Jun;5(6):636-40. doi: 10.3171/2010.2.PEDS09294.

Abstract

Pineal tumors are rare neoplasms that are categorized into pineoblastomas, pineocytomas, and pineal parenchymal tumors of intermediate differentiation. Pineal anlage tumors are primary pineal tumors with neuroepithelial and ectomesenchymal differentiation and without endodermal differentiation. The authors review the literature and report the case of a 5-month-old boy with a pineal anlage tumor. This is only the sixth case of a pineal anlage tumor reported in the English-language literature adding to the understanding of this tumor's presentation, immunomorphological and molecular characteristics, embryological origin, radiological appearance, treatment outcome, and prognosis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Biomarkers, Tumor / analysis
  • Biopsy
  • Chemotherapy, Adjuvant
  • Combined Modality Therapy
  • Craniotomy
  • Diagnosis, Differential
  • Emergencies*
  • Humans
  • Hydrocephalus / diagnosis
  • Hydrocephalus / pathology
  • Hydrocephalus / surgery
  • Infant
  • Magnetic Resonance Imaging
  • Male
  • Neuroectodermal Tumor, Melanotic / diagnosis
  • Neuroectodermal Tumor, Melanotic / drug therapy
  • Neuroectodermal Tumor, Melanotic / pathology
  • Neuroectodermal Tumor, Melanotic / surgery*
  • Neuroendoscopy
  • Neurologic Examination
  • Pineal Gland / pathology
  • Pineal Gland / surgery
  • Pinealoma / diagnosis
  • Pinealoma / drug therapy
  • Pinealoma / pathology
  • Pinealoma / surgery*
  • Tomography, X-Ray Computed
  • Ventriculostomy

Substances

  • Biomarkers, Tumor