Absence of the septum pellucidum associated with a midline fornical nodule and ventriculomegaly: a report of two cases

J Korean Med Sci. 2010 Jun;25(6):970-3. doi: 10.3346/jkms.2010.25.6.970. Epub 2010 May 24.

Abstract

We report two autopsy cases that revealed the partial absence of the septum pellucidum with ventriculomegaly. In each case, the brain showed mild dilatation of both frontal horns of the lateral ventricles, normal third and fourth ventricles and no aqueductal stenosis. The posterior portion of the septum pellucidum was absent and the fornices were fused in a single midline nodule, abnormally displaced to a caudal position and lodged in the foramina of Monro. The brain base showed no apparent abnormalities; the optic nerves were well developed. We conclude that the caudally displaced fornix in the absence of the septum pellucidum may have intermittently obstructed the foramina of Monro and induced mild ventriculomegaly.

Keywords: Fornix, Brain; Hydrocephalus; Septum Pellucidum; Ventriculomegaly.

Publication types

  • Case Reports

MeSH terms

  • Abortion, Induced
  • Adult
  • Cerebral Ventricles / abnormalities*
  • Dandy-Walker Syndrome / diagnostic imaging
  • Dandy-Walker Syndrome / pathology
  • Dilatation, Pathologic / diagnostic imaging
  • Female
  • Fetal Diseases / diagnostic imaging
  • Fetal Diseases / pathology
  • Fornix, Brain / abnormalities*
  • Gestational Age
  • Humans
  • Pregnancy
  • Septum Pellucidum / abnormalities*
  • Septum Pellucidum / diagnostic imaging
  • Septum Pellucidum / pathology
  • Ultrasonography, Prenatal