Determinants of frailty

J Am Med Dir Assoc. 2010 Jun;11(5):356-64. doi: 10.1016/j.jamda.2009.11.008.

Abstract

Objectives: To determine which determinants predict frailty and domains of frailty (physical, psychological, social) in a community-dwelling sample of elderly persons.

Design: Cross-sectional.

Setting: Community-based.

Participants: A representative sample of 484 community-dwelling persons aged 75 years and older.

Measurements: The Tilburg Frailty Indicator (TFI), a self-report questionnaire, was used to collect information about determinants of frailty and to assess frailty and domains of frailty (physical, psychological, social).

Results: Results were obtained by regression and mediation analyses. The 10 determinants explain about 35% of the variance of frailty. After controlling for other determinants, medium income, an unhealthy lifestyle, and multimorbidity predicted frailty. The effects of other determinants differed across domains of frailty; age predicted physical frailty, life events predicted psychological frailty, whereas being a woman predicted social frailty because older women have a higher probability of living alone.

Conclusion: Our finding that the effect of the determinants of frailty differs across frailty domains suggests that it is essential to divide the concept of frailty into domains.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Cross-Sectional Studies
  • Female
  • Frail Elderly* / psychology
  • Frail Elderly* / statistics & numerical data
  • Health Status*
  • Humans
  • Male
  • Netherlands
  • Surveys and Questionnaires*